A UEFA Champions League winner with Chelsea, goalkeeper Petr Čech is the latest centurion in our series.
The Barcelona forward has reached a half-century of career hat-tricks; UEFA.com takes a closer look.
Barcelona are in a record 12th straight quarter-final while Ajax end a 16-year absence: all the last eight's past ties.
Arsenal are forging on after overturning a two-goal defeat, while Frankfurt and Slavia Praha secured great wins.
Lionel Messi scored twice and set up two other goals as Barcelona booked a last-eight place for the 12th successive season.
Manuel Neuer has joined the exclusive club of players with 100 or more UEFA Champions League appearances.
Sadio Mané and Virgil van Dijk struck late to seal Liverpool's progress to the quarter-finals.
Manchester City turned on the style to record their biggest ever European win and reach the last eight.
Cristiano Ronaldo has 125 and Lionel Messi over 100, but who else has reached a half century?
Bayern and Liverpool are deadlocked at 0-0 going into a game "the whole world will be watching".
Cristiano Ronaldo plundered his eighth UEFA Champions League hat-trick as Juventus turned around the tie.
Karim Benzema became the fourth player to reach 60 UEFA Champions League goals on Wednesday.
Iker Casillas remains out in front although Cristiano Ronaldo is threatening to catch his one-time team-mate.
Juventus must overturn a 2-0 deficit but Cristiano Ronaldo is no stranger to scoring against Atlético Madrid.
Zinédine Zidane is back for a second spell as Real Madrid coach. Where does he stand in the UEFA Champions League pantheon?
The quarter-final draw will be live on UEFA.com from 13:00CET on Friday – here are all the details.
Manchester City hold a 3-2 lead at home as Schalke come to town off the back of a four-game losing run.
Diego Godín can make his 100th UEFA club competition appearance this week; UEFA.com gives due respect.
"There's always pressure at a big club," says Liverpool defensive leader Virgil van Dijk.
Both Chelsea and Napoli have three players in this week's selection; who else makes the cut?
Arsenal have plenty of work to reach a second successive quarter-final as they attempt to retrieve a 3-1 defeat at Rennes.
Manchester United and Porto are the latest teams into the UEFA Champions League quarter-finals.
Chelsea took command of the tie with a 3-0 first-leg win in London, leaving Dynamo with plenty to do on home soil.
Napoli seized control with a 3-0 first-leg win against Salzburg and will look to seal a quarter-final place in Austria.
Petr Čech's return to Rennes did not go to plan, but Chelsea and Napoli took firm control of their ties at home.
Manchester United and Porto are the latest team into the UEFA Champions League quarter-finals.
Porto produced a spirited performance to beat Roma after extra time and book a place in the last eight.
Marcus Rashford struck a last-gasp penalty as United made UEFA Champions League history.
He's a fleet-footed winger likened to Arjen Robben; meet Villarreal's new star Samuel Chukwueze.
Paris Saint-Germain defend a 2-0 lead at home to a Manchester United team without a number of key players.
"There is no rush," says Porto coach Sérgio Conceição as they seek to overturn a 2-1 deficit against Roma.
Harry Kane scored the only goal as Tottenham eased into the quarter-finals with a second win over Dortmund.
Ajax and Tottenham are the first two teams through to the UEFA Champions League quarter-finals.
Ajax are through to the quarter-finals after a stunning 4-1 win at Real Madrid.
Real Madrid look to bounce back from two home losses against Barcelona while Ajax seek to overturn a 2-1 deficit.
Borussia Dortmund need to do something they have never done before and overturn a three-goal deficit.
There is no shortage of former winners in the hunt for the UEFA Europa League trophy; will they make it to the last eight?
This is already Rennes' most successful European campaign; next up, continental heavyweights Arsenal come to Brittany.
Sevilla's quest for a fourth UEFA Europea League triumph continues against Slavia Praha, conquerors of Genk in the last 32.
Zenit got the better of Villarreal in 2007/08 and will be looking for a repeat performance this season.
Manchester United and Borussia Dortmund have difficult tasks in the second legs, but they can take hope.